Angiotensin II, ATP and high extracellular potassium induced intracellular calcium responses in primary rat brain endothelial cell cultures

CA García‐Carlos, JA Camargo‐Loaiza… - Cell Biochemistry …, 2021 - Wiley Online Library
… Ang II can modulate vessel responses in response to tissue … BK channels are modulated
by diverse signalling pathways, … A and C, and other molecules like nitric oxide, fatty acids (ω-3 …

HSP90 modulates T2R bitter taste receptor nitric oxide production and innate immune responses in human airway epithelial cells and macrophages

RM Carey, BM Hariri, ND Adappa, JN Palmer, RJ Lee - Cells, 2022 - mdpi.com
… We also tested CBF response to HBSS that had been conditioned by overnight exposure
to … with conditioned LB medium and showed that CBF increases in response to dilute (6.25–12…

Astrocyte Regulation of Cerebral Blood Flow in Health and Disease

A Mishra, GR Gordon… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
… Raising extracellular K+ concentration ([K+]o) from a resting … generation of nitric oxide (NO)
via neuronal nitric oxide synthase (… the polarity of astrocyte modulation of CBF may reflect the …

Nitric oxide (NO) modulates low temperature-stress signaling via S-nitrosation, a NO PTM, inducing ethylene biosynthesis inhibition leading to enhanced post-harvest …

Y Sougrakpam, P Babuta, R Deswal - Physiology and Molecular Biology of …, 2023 - Springer
Low temperature (cold) stress is one of the major abiotic stress conditions affecting crop
productivity worldwide. Nitric oxide (NO) is a dynamic signaling molecule that interacts with …

Nitric oxide and the brain. Part 1: Mechanisms of regulation, transport and effects on the developing brain

D Angelis, R Savani, L Chalak - Pediatric Research, 2021 - nature.com
… After brain hypoxia/ischemia and reperfusion, both nNOS and eNOS participate in the
modulation of CBF. In Table 1a, we summarize data from key animal studies that show the role of …

Neuropeptide Y Reduces Nasal Epithelial T2R Bitter Taste Receptor–Stimulated Nitric Oxide Production

RM Carey, ND Adappa, JN Palmer, RJ Lee - Nutrients, 2021 - mdpi.com
… be increased in some sinonasal diseases. We hypothesized that NPY modulates cilia-localized
T2R responses … -mediated NO production and CBF responses. This likely occurs through …

Simultaneous functional near-infrared spectroscopy (fNIRS) and electroencephalogram (EEG) to elucidate neurovascular modulation by transcranial electrical …

A Dutta - Brain Stimulation: Basic, Translational, and Clinical …, 2021 - brainstimjrnl.com
… mechanisms of tDCS-evoked CBF response are unknown. A … Here, extracellular potassium
can interact with the calcium … -dependent synthesis of nitric oxide crucial for local vasodilatory …

Dual role of nitric oxide in Alzheimer's Disease

A Azargoonjahromi - Nitric Oxide, 2023 - Elsevier
… The modulation of baseline CBF and cerebrovascular reactions to metabolic activity and
hypercapnia are processes in which NO functions the CNS [59,83]. Some studies have …

Focal Brain Cooling Suppresses Spreading Depolarization and Reduces Endothelial Nitric Oxide Synthase Expression in Rats

Y Hirayama, H Kida, T Inoue, K Sugimoto… - Available at SSRN … - papers.ssrn.com
High extracellular potassium concentrations disturb astrocytes and neurons, triggering SD
and leading to changes in cerebral blood flow (CBF… SD by combining the modulation of neural …

Dietary nitrate supplementation and cognitive health: the nitric oxide-dependent neurovascular coupling hypothesis

JS Gonçalves, AL Marçal, BS Marques… - Biochemical Society …, 2024 - portlandpress.com
… Dietary nitrate as a fuel for nitric oxide-modulated signaling … pathways and physiological
responses is nitric oxide ( • NO), … the infarct volume, enhanced CBF, and improved cognitive …